Omega Therapeutics, Inc. (Nasdaq: OMGA), a development-stage biotechnology company pioneering the first systematic approach to use mRNA therapeutics as a new class of programmable epigenetic medicines by leveraging its OMEGA Epigenomic Programing platform, today announced the appointment of Yan Moore, M.D., as Chief Medical Officer. Dr. Moore has extensive management, research, translational drug development and medical affairs experience across various pharmaceutical and biotechnology companies.
“I am thrilled to welcome Yan to the team and look forward to leveraging his broad clinical development and medical expertise as we transition into a clinical stage company while continuing to develop our epigenomic programming platform across broad therapies to cure and prevent diseases,” said Mahesh Karande, President and Chief Executive Officer of Omega Therapeutics. “Yan joins our team at a pivotal time as we remain focused on advancing our lead program, OTX-2002 targeting c-MYC for the treatment of hepatocellular carcinoma, into the clinic and nominating additional development candidates in 2022.”
“The OMEGA Epigenomic Programming platform has the potential to provide meaningful, disease modifying treatments to patients and families in need,” said Dr. Moore. “I look forward to being a part of the Omega team to help advance these treatments into the clinic, expand programs in development and help realize the company’s aspirations of bringing pioneering programmable epigenetic medicines to patients in need.”
Dr. Moore most recently served as Senior Vice President, Head of Oncology Therapeutic Area at Ipsen Pharmaceuticals where he focused on scientific and development strategy as well as identifying and executing on research and development objectives in the areas of oncology and immune-modulatory therapies. Before Ipsen, Dr. Moore was the Chief Medical Officer and Senior Vice President of Clinical Development and Research and Development at Anchiano Therapeutics (previously BioCanCell Therapeutics), where he played a key role in managing clinical and preclinical drug development, worked alongside regulatory agencies to design clear paths to regulatory approval, developed commercialization plans and managed global medical affairs strategy. Earlier in his career, Dr. Moore held various roles of increasing responsibility spanning global medical affairs and clinical development at Ariad, Sanofi, GlaxoSmithKline and Bristol Myers-Squibb. As a clinician, Dr. Moore spent time at Sapir Medical Center, Meir Hospital and Edith Wolfson Medical Center.
Dr. Moore received his Medical degree and Bachelor of Medical Sciences from the Sackler School of Medicine at Tel Aviv University, Master of Business Administration from the LeBow College of Business at Drexel University, and completed the Advanced Management Program at Harvard Business School.
About Omega Therapeutics
Omega Therapeutics, founded by Flagship Pioneering, is a development-stage biotechnology company pioneering the first systematic approach to use mRNA therapeutics as a new class of programmable epigenetic medicines. The company’s OMEGA Epigenomic Programming™ platform harnesses the power of epigenetics, the mechanism that controls gene expression and every aspect of an organism’s life from cell genesis, growth, and differentiation to cell death. Using a suite of technologies, paired with Omega’s process of systematic, rational, and integrative drug design, the deterministic OMEGA platform enables control of fundamental epigenetic processes to correct the root cause of disease by returning aberrant gene expression to a normal range without altering native nucleic acid sequences. Omega’s modular and programmable mRNA epigenetic medicines, Omega Epigenomic Controllers™, target specific epigenomic loci within insulated genomic domains, EpiZips™, from amongst thousands of unique, mapped, and validated genome-wide DNA-sequences, with high specificity to durably tune single or multiple genes to treat and cure diseases through Precision Genomic Control™. Omega is currently advancing a broad pipeline of development candidates spanning a range of disease areas, including oncology, regenerative medicine, multigenic diseases including immunology, and select monogenic diseases.
For more information, visit omegatherapeutics.com, or follow us on Twitter and LinkedIn.
