Lexicon Elects Diane E. Sullivan to Board of Directors

THE WOODLANDS, Texas, July 28, 2023 (GLOBE NEWSWIRE) — Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that Diane E. Sullivan has been elected to its Board of Directors.

Ms. Sullivan brings extensive commercialization, strategy, and market access experience to the Lexicon Board of Directors. She was chief commercial officer of The Medicines Company until its acquisition by Novartis, and subsequently served as chief commercial officer at DalCorp Pharmaceuticals. Prior to her time at The Medicines Company, Ms. Sullivan held senior positions at AstraZeneca, Pfizer, Wyeth, and GlaxoSmithKline in a variety of disciplines, including market access, strategy, marketing, brand management, business development and integration.

“I am looking forward to contributing to the company’s important mission of pioneering medicines that transform patients’ lives and helping to provide strategic direction to the company’s commercial launch of INPEFA (sotagliflozin) and advancement of its pipeline,” said Ms. Sullivan.

Ms. Sullivan served as a director of OrthogenRx, a privately held medical device company, until it was acquired by Avanos Medical in January 2022 and currently serves as a director of Amarin. Ms. Sullivan received her B.A. from Dickinson College.

Ms. Sullivan’s appointment is concurrent with the resignation from the Lexicon Board of Directors of Frank Palantoni after 18 years of service culminating in the approval of INPEFA.

“We are grateful to Frank for his service on the Board of Directors and appreciate his contributions to the company’s progress,” said Ray Debbane, Lexicon’s Board Chair. “With Diane’s appointment, I am confident that the extensive pharmaceutical commercial experience she brings will provide Lexicon with valuable insight and direction as we pursue our launch of INPEFA and gear up for the advancement of our LX9211 clinical program. We are very excited to have Diane join the Board of Directors.”

About Lexicon Pharmaceuticals

Lexicon is a biopharmaceutical company with a mission of pioneering medicines that transform patients’ lives. Through its Genome5000™ program, Lexicon scientists studied the role and function of nearly 5,000 genes and identified more than 100 protein targets with significant therapeutic potential in a range of diseases. Through the precise targeting of these proteins, Lexicon is pioneering the discovery and development of innovative medicines to treat diseases safely and effectively. Lexicon is commercially launching one of these medicines, INPEFA (sotagliflozin), in the United States and has a pipeline of other promising drug candidates in discovery and preclinical and clinical development in neuropathic pain, diabetes and metabolism and other indications. For additional information, please visit www.lexpharma.com.

About INPEFA (sotagliflozin)

Discovered using Lexicon’s unique approach to gene science, INPEFA (sotagliflozin) is an oral inhibitor of two proteins responsible for glucose regulation known as sodium-glucose cotransporter types 2 and 1 (SGLT2 and SGLT1). SGLT2 is responsible for glucose reabsorption by the kidney and SGLT1 is responsible for glucose absorption in the gastrointestinal tract. Sotagliflozin has been studied in multiple patient populations encompassing heart failure, diabetes, and chronic kidney disease in clinical studies involving approximately 20,000 patients.